Selection for gamete lethals and S-alleles in complex heterozygotes

Selection against Heterozygotes for a Utosomal Lethals in Natural Populations of Drosophila

locality being treated separately and the sums of squares then combined. Since this analysis of variance showed significant differences between different combinations of chromosomes, for further work the average of the frequencies of wild-type flies for the different cultures of a single combination of chromosomes was considered as the basic variable. Then Star/Lethal X Normal/Normal at Emboaba...

Editorial: “Disease-Only” alleles and genotypes in complex disorders?

Selection for heterozygotes in small populations.

I N his mathematical analyses of evolutionary processes WRIGHT ( 193 1, 1937) has given particular attention to the interaction of population size with the factors of selection, mutation and migration. Here he introduced the powerful concept of the "gene frequency distribution" which may be thought of as referring either to similar loci in the same population or one locus in many populations. I...

’s syndrome heterozygotes in Japan

Werner’s syndrome is an autosomal recessive disease that causes premature ageing accompanied by an increased susceptibility to cancer. The causative gene (W R N) codes for a DNA helicase. Worldwide, 1200 patients have been reported from 1904 to 1996; 845 from Japan. Patients are distributed all over Japan. But how widely distributed is the mutated WRN gene in the general population? We previous...

passivity in waiting for godot and endgame: a psychoanalytic reading

this study intends to investigate samuel beckett’s waiting for godot and endgame under the lacanian psychoanalysis. it begins by explaining the most important concepts of lacanian psychoanalysis. the beckettian characters are studied regarding their state of unconscious, and not the state of consciousness as is common in most beckett studies. according to lacan, language plays the sole role in ...